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. 2019 Jun 7;7:9. doi: 10.1186/s40478-019-0743-1

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — AD Neuropathologic change. Cases were selected based on the degree of AD neuropathologic change. The resistant cases were selected based on a Braak score of III or less and absent neuritic plaques by CERAD criteria. Their AD dementia matches, the resilient cases, and their respective AD dementia matches were selected based on a Braak stage VI and frequent neuritic plaques. Re-evaluation demonstrated the expected distribution of amyloid plaques (a), neurofibrillary tangles (b), and density of neuritic plaques (c), based on these selection criteria