. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Bioorg Med Chem. 2019 Mar 19;27(9):1845–1854. doi: 10.1016/j.bmc.2019.03.034

Table 1:

Minimum inhibitory concentration (MIC, in µM) of second-generation aryl isonitrile analogues and control antibiotics against methicillin-resistant Staphylococcus aureus (MRSA) NRS123 (USA400).

Compound/Drug Name	MRSA NRS123 (USA 400)
Compound/Drug Name	MIC
6	32
7	2
8	64
9	32
10	64
11	>64
12	32
13	8
14	>64
17	16
18	4
19	8
21	>64
22	32
23	>64
24	64
25	>64
26	>64
27	16
28	32
Linezolid	1
Vancomycin	1

N.D. = Not determined