Figure 3.

Effect of Lycium barbarum polysaccharide (LBP) on cerulein-induced acute pancreatitis (AP) in wild-type (WT) or nuclear factor erythroid-2-related factor 2 (NRF2) gene knockout mice (NRF2−/−). (A) Production of reactive oxygen species (ROS). (B) Nuclear Nrf2 expression. (C) Heme oxygenase (HO-1), and (D) superoxide dismutase (SOD) expression in the pancreas. Values shown are the mean ±SEM. * P<0.05, when compared with WT sham mice treated with NS. ^# P<0.05, when compared with the WT mice with AP treated with NS. NS – normal saline.