Effect of compressive force on mRNA levels of osteoclastic bone resorption-related enzymes in RAW264.7 cells. The mRNA expression levels of carbonic anhydrase II (A), matrix metalloproteinase-9 (B), and cathepsin K (C) were determined by real-time RT-PCR on days 3 and 4 of culture. Bars indicate the means ± standard deviation of 4 independent experiments. * P<0.05, ** P<0.01, *** P<0.001 (vs. 0.3 g/cm2), ## P<0.01 (0.6 vs. 1.1 g/cm2).