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. 2019 May 26;25:3910–3917. doi: 10.12659/MSM.914338

Table 2.

Comparison of biochemical values in the three study groups, the control group, the untreated group with polycystic ovary syndrome (PCOS), and the PCOS group treated with clomiphene citrate (PCOS-CC).

Diagnosis N Mean ±SD P-value Post-hoc p-value
TSH (IU/L) Control 25 2.46±0.60 2.44 (1.22–3.67) 0.247a
PCOS 24 2.75±0.69 2.68 (1.36–3.99)
PCOS-CC 26 2.72±0.70 2.76 (1.25–3.98)
FSH (IU/L) Control 25 4.94±1.74 4.21 (2.54–8.74) 0.720b
PCOS 24 4.72±1.82 4.23 (2.14–9.34)
PCOS-CC 26 4.73±1.96 3.90 (2.61–8.85)
LH (IU/L) Control (1) 25 3.97±1.76 3.55 (1.87–8.58) <0.001*b 1–2: 0.001*
PCOS (2) 24 6.30±1.98 6.06 (3.74–11.41) 1–3: <0.001*
PCOS-CC (3) 26 7.15±2.18 6.44 (3.99–11.32) 2–3: 0.835
E2 (pg/ml) Control 25 101.32±25.04 100.00 (44,25–136.66) 0.808b
PCOS 24 98.95±20.80 100.23 (39.76–132.22)
PCOS-CC 26 97.26±19.13 100.27 (56.87–121.25)
HDL (mg/dl) Control 25 55.72±5.39 55.56 (43.64–69.00) 0.627a
PCOS 24 57.19±6.37 56.96 (44.00–6.00)
PCOS-CC 26 56.86±5.04 56.77 (49.69–66.87)
LDL (mg/dl) Control 25 111.21±13.00 111.21 (85.58–130.00) <0.001*b 1–2: 0.002*
PCOS 24 125.02±9.77 125.34 (96.25–141.25) 1–3: <0.001*
PCOS-CC 26 127.04±9.24 128.52 (100.33–141.00) 2–3: 1.000
HOMA Control 25 2.05±0.25 2.02 (1.34–2.45) <0.001*b 1–2: 0.001*
PCOS 24 2.36±0.29 2.36 (1.54–2.87) 1–3: 0.001*
PCOS-CC 26 2.40±0.46 2.43 (1.45–3.50) 2–3: 1.000
BMI (kg/m2) Control 25 21.62±1.10 21.25 (20.00–24.96) <0.001*b 1–2: <0.001*
PCOS 24 24.43±2.43 24.28 (19.98–29.25) 1–3: 0.001*
PCOS-CC 26 24.29±3.17 24.39 (18.65–29.58) 2–3: 1.000
FER-GAL Control 25 2,.9±1.05 2.20 (2.00–5.00) <0.001*b 1–2: <0.001*
PCOS 24 8.77±2.60 8.87 (4.40–12.25) 1–3: <0.001*
PCOS-CC 26 10.15±2.43 10.00 (5.00–14.00) 2–3: 0.725
a

ANOVA, analysis of variance;

b

Kruskall-Wallis test;

TSH – thyroid stimulating hormone; FSH – follicular stimulating hormone; LH – luteinizing hormone; E2 – estradiol; BMI – body mass index; FERGAL – Ferriman-Gallwey score.