Table 2.
Comparison of biochemical values in the three study groups, the control group, the untreated group with polycystic ovary syndrome (PCOS), and the PCOS group treated with clomiphene citrate (PCOS-CC).
Diagnosis | N | Mean ±SD | P-value | Post-hoc p-value | ||
---|---|---|---|---|---|---|
TSH (IU/L) | Control | 25 | 2.46±0.60 | 2.44 (1.22–3.67) | 0.247a | – |
PCOS | 24 | 2.75±0.69 | 2.68 (1.36–3.99) | |||
PCOS-CC | 26 | 2.72±0.70 | 2.76 (1.25–3.98) | |||
FSH (IU/L) | Control | 25 | 4.94±1.74 | 4.21 (2.54–8.74) | 0.720b | – |
PCOS | 24 | 4.72±1.82 | 4.23 (2.14–9.34) | |||
PCOS-CC | 26 | 4.73±1.96 | 3.90 (2.61–8.85) | |||
LH (IU/L) | Control (1) | 25 | 3.97±1.76 | 3.55 (1.87–8.58) | <0.001*b | 1–2: 0.001* |
PCOS (2) | 24 | 6.30±1.98 | 6.06 (3.74–11.41) | 1–3: <0.001* | ||
PCOS-CC (3) | 26 | 7.15±2.18 | 6.44 (3.99–11.32) | 2–3: 0.835 | ||
E2 (pg/ml) | Control | 25 | 101.32±25.04 | 100.00 (44,25–136.66) | 0.808b | – |
PCOS | 24 | 98.95±20.80 | 100.23 (39.76–132.22) | |||
PCOS-CC | 26 | 97.26±19.13 | 100.27 (56.87–121.25) | |||
HDL (mg/dl) | Control | 25 | 55.72±5.39 | 55.56 (43.64–69.00) | 0.627a | – |
PCOS | 24 | 57.19±6.37 | 56.96 (44.00–6.00) | |||
PCOS-CC | 26 | 56.86±5.04 | 56.77 (49.69–66.87) | |||
LDL (mg/dl) | Control | 25 | 111.21±13.00 | 111.21 (85.58–130.00) | <0.001*b | 1–2: 0.002* |
PCOS | 24 | 125.02±9.77 | 125.34 (96.25–141.25) | 1–3: <0.001* | ||
PCOS-CC | 26 | 127.04±9.24 | 128.52 (100.33–141.00) | 2–3: 1.000 | ||
HOMA | Control | 25 | 2.05±0.25 | 2.02 (1.34–2.45) | <0.001*b | 1–2: 0.001* |
PCOS | 24 | 2.36±0.29 | 2.36 (1.54–2.87) | 1–3: 0.001* | ||
PCOS-CC | 26 | 2.40±0.46 | 2.43 (1.45–3.50) | 2–3: 1.000 | ||
BMI (kg/m2) | Control | 25 | 21.62±1.10 | 21.25 (20.00–24.96) | <0.001*b | 1–2: <0.001* |
PCOS | 24 | 24.43±2.43 | 24.28 (19.98–29.25) | 1–3: 0.001* | ||
PCOS-CC | 26 | 24.29±3.17 | 24.39 (18.65–29.58) | 2–3: 1.000 | ||
FER-GAL | Control | 25 | 2,.9±1.05 | 2.20 (2.00–5.00) | <0.001*b | 1–2: <0.001* |
PCOS | 24 | 8.77±2.60 | 8.87 (4.40–12.25) | 1–3: <0.001* | ||
PCOS-CC | 26 | 10.15±2.43 | 10.00 (5.00–14.00) | 2–3: 0.725 |
ANOVA, analysis of variance;
Kruskall-Wallis test;
TSH – thyroid stimulating hormone; FSH – follicular stimulating hormone; LH – luteinizing hormone; E2 – estradiol; BMI – body mass index; FERGAL – Ferriman-Gallwey score.