. 2019 May 26;25:3910–3917. doi: 10.12659/MSM.914338

Table 3.

Comparison of the total oxidative status (TOS), total antioxidant status (TAS), and levels of paraoxonase (PON) before and after day 21 of the menstrual cycle in women with polycystic ovary syndrome (PCOS) treated with clomiphene citrate to induce ovulation.

Diagnosis		N	Mean ±SD	p-Value
Control	TAS-3	25	1.40±0.07	<0.001^*
	TAS-21	25	1.31±0.09	<0.001^*
	TOS-3	25	18.99±3.20	<0.001^*
	TOS-21	25	21.23±3.69	<0.001^*
	PON-3	25	138.55±17.80	<0.001^*
	PON-21	25	132.52±17.74	<0.001^*
PCOS	TAS-3	24	1.15±0.06	<0.001^*
	TAS-21	24	1.06±0.06	<0.001^*
	TOS-3	24	33.78±5.35	<0.001^*
	TOS-21	24	37.22±5.08	<0.001^*
	PON-3	24	79.01±17.24	<0.001^*
	PON-21	24	73.12±15.27	<0.001^*
PCOS-CC	TAS-3	26	1.18±0.06	<0.001^*
	TAS-21	26	1.08±0.078	<0.001^*
	TOS-3	26	35.47±5.21	<0.001^*
	TOS-21	26	38.76±4.40	<0.001^*
	PON-3	26	73.62±15.94	<0.001^*
	PON-21	26	67.24±1,26	<0.001^*

Paired t-test.

PCOS – polycystic ovary syndrome (untreated); TOS – total oxidative status; TAS – total antioxidant status; PCOS-CC – patients with PCOS treated with clomiphene citrate; PON – paraoxonase; TAS-3 – TAS value on the day 3 of the menstrual cycle; TAS-21 – TAS value on day 21 of the menstrual cycle; TOS-3 – TOS value on day 3 of the menstrual cycle; TOS-21 – TOS value on day 21 of the menstrual cycle; PON-3 – PON-1 value on day 3 of the menstrual cycle; PON-21 – PON-1 value on day 21 of the menstrual cycle.