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Composition of the simulation medium in simulated fast-state gastric fluid (FaSSGF) fed-state simulated gastric fluid (FeSSGF)
| FaSSGF | FeSSGF | |
|---|---|---|
| Composition | ||
| Sodium taurocholate (μM) | 80 | – |
| Lecithin (μM) | 20 | – |
| Pepsin (mg/mL) | 0.1 | – |
| Sodium chloride (mM) | 34.2 | 237.2 |
| Acetic acid (mM) | – | 17.12 |
| Sodium acetate (mM) | – | 29.75 |
| Milk/acetate buffer | – | 1:1 |
| Hydrochloric acid q.s. pH | 1.6 | 5.0 |
| Properties | ||
| pH | 1.6 | 5.0 |
| Osmolality (mOsm/kg) | 120.7 ± 2.5 | 400 |
| Buffer capacity (mmol/L/pH) | – | 25 |
| Surface tension (mN/m) | 42.6 | – |
