Table 2.
25(OH)D (N=318)1 |
1,25(OH)2D (N=318)1 |
iPTH (N=318)1 |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | ||||||||
Variable2 | N | r | P | r | P | r | P | r | P | r | P | r | P |
Fat-Free Soft Tissue (kg) | 320 | −0.12 | 0.038 | −0.02 | 0.826 | 0.12 | 0.037 | 0.10 | 0.130 | 0.12 | 0.037 | 0.15 | 0.030 |
Handgrip Strength (kg) | 303 | −0.21 | <0.001 | 0.04 | 0.602 | 0.14 | 0.019 | 0.12 | 0.083 | 0.21 | 0.001 | 0.07 | 0.25 |
Forearm MCSA (mm2) | 321 | −0.32 | <0.01 | −0.02 | 0.826 | 0.13 | 0.028 | 0.12 | 0.270 | 0.23 | <0.001 | 0.15 | 0.022 |
Forearm MD (mg/cm3) | 321 | 0.34 | <0.001 | 0.09 | 0.166 | −0.04 | 0.509 | −0.03 | 0.620 | −0.12 | 0.034 | <0.01 | 0.99 |
Forearm IMAT (mm2) | 297 | −0.33 | <0.001 | −0.04 | 0.517 | 0.10 | 0.101 | 0.04 | 0.529 | 0.13 | 0.034 | 0.07 | 0.314 |
Calf MCSA (mm2) | 317 | −0.13 | 0.026 | −0.06 | 0.356 | 0.12 | 0.040 | 0.08 | 0.233 | 0.18 | 0.001 | 0.12 | 0.066 |
Calf MD (mg/cm3) | 318 | 0.39 | <0.01 | 0.11 | 0.103 | 0.01 | 0.934 | <0.01 | 0.948 | −0.16 | 0.006 | −<0.01 | 0.962 |
Calf IMAT (mm2) | 308 | −0.21 | <0.01 | −0.08 | 0.230 | 0.12 | 0.045 | 0.06 | 0.349 | 0.13 | 0.030 | 0.07 | 0.268 |
Partial correlations of unadjusted and adjusted (for race, sex, age, and latitude, N=223) between vitamin D metabolites and muscle-related outcomes. Statistically significant if P ≤ 0.05 and in bold font. Partial Correlation Coefficient (r) displays strength of correlation. MCSA, muscle cross-sectional area; MD, muscle density; IMAT, intermuscular adipose tissue