Table 4.
25(OH)D (N=302)1 |
1,25(OH)2D (N=302)1 |
iPTH (N=302)1 |
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted | ||||||||
ΔMuscle Outcomes2 | N | r | P | r | P | r | P | r | P | r | P | r | P |
Fat-Free Soft Tissue (kg) | 300 | −0.04 | 0.564 | −0.03 | 0.688 | <0.01 | 0.975 | 0.03 | 0.718 | <0.01 | 0.975 | 0.10 | 0.231 |
Handgrip Strength (kg) | 285 | 0.04 | 0.585 | 0.02 | 0.841 | 0.07 | 0.270 | 0.10 | 0.214 | 0.05 | 0.439 | <0.01 | 0.956 |
Forearm MCSA (mm2) | 299 | 0.03 | 0.666 | −0.05 | 0.560 | 0.11 | 0.077 | 0.08 | 0.321 | 0.10 | 0.103 | 0.19 | 0.019 |
Forearm MD (mg/cm3) | 299 | 0.04 | 0.478 | 0.06 | 0.462 | −0.03 | 0.652 | 0.01 | 0.862 | 0.01 | 0.939 | 0.01 | 0.922 |
Forearm IMAT (mm2) | 265 | −0.05 | 0.487 | −0.17 | 0.029 | 0.09 | 0.139 | 0.01 | 0.913 | 0.13 | 0.039 | 0.17 | 0.029 |
Calf MCSA (mm2) | 296 | 0.01 | 0.858 | −0.04 | 0.581 | 0.09 | 0.154 | −0.07 | 0.376 | 0.18 | 0.002 | 0.19 | 0.016 |
Calf MD (mg/cm3) | 296 | −0.05 | 0.424 | −0.10 | 0.192 | 0.02 | 0.693 | 0.07 | 0.362 | −0.10 | 0.104 | −0.07 | 0.414 |
Calf IMAT (mm2) | 280 | 0.06 | 0.386 | 0.04 | 0.612 | 0.03 | 0.678 | −0.08 | 0.305 | 0.14 | 0.029 | 0.16 | 0.037 |
Partial correlations of unadjusted and adjusted (for race, sex, age, and latitude, N =239) between N Vitamin D metabolites and muscle-related outcomes. Statistically significant if P ≤ 0.05 and in bold font. Partial Correlation Coefficient (r) displays strength of correlation.
MCSA, muscle cross-sectional area; MD, muscle density; IMAT, intermuscular adipose tissue.