Table 4.

Metabolites significantly associated with NDM/LDM and with a circulating marker of carbamylation.

	β ± SE	p-Value	q-Value
C-glycosyltryptophan	0.2 ± 0.0	8.8E − 07	2.2E − 05
Erythronate	0.1 ± 0.0	1.6E − 06	3.5E − 05
N1-methyladenosine	0.2 ± 0.0	1.1E − 05	0.0001
N-acetylthreonine	0.1 ± 0.0	1.1E − 05	0.0001
Pseudouridine	0.1 ± 0.0	1.8E − 05	0.0002
2-Hydroxyisobutyrate	0.1 ± 0.0	2.3E − 05	0.0003
N-acetylalanine	0.2 ± 0.0	2.6E − 05	0.0003
2-Methylbutyroylcarnitine	0.1 ± 0.0	0.0002	0.002
4-Acetamidobutanoate	0.1 ± 0.0	0.0002	0.002
Threitol	0.1 ± 0.0	0.0002	0.002
N-formylmethionine	0.i ± 0.0	0.0002	0.002
Glutamine	− 0.2 ± 0.0	0.0004	0.003
Myo-inositol	0.1 ± 0.0	0.0004	0.003
Urea	0.1 ± 0.0	0.001	0.007
Phenylacetylglutamine	0.0 ± 0.0	0.001	0.007
Tiglyl carnitine	0.1 ± 0.0	0.001	0.008
Erythritol	0.1 ± 0.0	0.001	0.008
Arabonate	0.0 ± 0.0	0.003	0.01
Glutaroyl carnitine	0.1 ± 0.0	0.003	0.01
Isobutrylcarnitine	0.0 ± 0.0	0.003	0.01
Dimethylglycine	0.1 ± 0.0	0.003	0.01
Serine	− 0.1 ± 0.0	0.01	0.05
N-acetylserine	0.1 ± 0.0	0.01	0.05
Methylglutarylcarnitine	0.0 ± 0.0	0.02	0.05
Asparagine	− 0.1 ± 0.0	0.02	0.06
Glucuronate	0.0 ± 0.0	0.02	0.07
Indolelactate	0.0 ± 0.0	0.02	0.07
N6-acetyllysine	0.1 ± 0.0	0.02	0.07
Arabitol	0.1 ± 0.0	0.02	0.07
Phenol sulfate	0.0 ± 0.0	0.03	0.07
Cis-4-decenoyl carnitine	0.0 ± 0.0	0.03	0.08
Butyrylcarnitine	0.0 ± 0.0	0.03	0.09
Hexanoylcarnitine	0.0 ± 0.0	0.04	0.09
Glycine	− 0.1 ± 0.0	0.04	0.09
Mannitol	0.0 ± 0.0	0.05	0.12

Metabolites significantly associated with NDM/LDM and with a circulating marker of carbamylation (homocitrulline/lysine) are shown with parameter estimates and standard errors (β ± SE), and with p- and q-values.