Table 5.
Metabolites significantly associated with NDM/LDM and with a circulating marker of immune activation.
| β ± SE | p-Value | q-Value | |
|---|---|---|---|
| C-glycosyltryptophan | 0.4 ± 0.1 | 4.4E − 09 | 2.5E − 07 |
| Erythritol | 0.3 ± 0.1 | 6.3E − 08 | 2.7E − 06 |
| Pseudouridine | 0.4 ± 0.1 | 1.2E − 07 | 4.2E − 06 |
| 1-Methylurate | 0.2 ± 0.0 | 8.0E − 07 | 2.1E − 05 |
| 4-Acetamidobutanoate | 0.3 ± 0.1 | 9.2E − 07 | 2.2E − 05 |
| N1-methyladenosine | 0.4 ± 0.1 | 2.5E − 06 | 4.7E − 05 |
| N-acetylalanine | 0.4 ± 0.1 | 3.2E − 06 | 5.6E − 05 |
| N-formylmethionine | 0.3 ± 0.1 | 4.8E − 06 | 7.3E − 05 |
| Arabonate | 0.1 ± 0.0 | 1.3E − 05 | 0.0002 |
| Urea | 0.2 ± 0.0 | 2.1E − 05 | 0.0002 |
| Phenylacetylglutamine | 0.1 ± 0.0 | 2.9E − 05 | 0.0003 |
| Erythronate | 0.2 ± 0.0 | 5.9E − 05 | 0.0006 |
| Myo-inositol | 0.2 ± 0.0 | 0.0001 | 0.0009 |
| Glutaroyl carnitine | 0.1 ± 0.0 | 0.0002 | 0.002 |
| 2-Hydroxyisobutyrate | 0.2 ± 0.0 | 0.0004 | 0.003 |
| Threitol | 0.1 ± 0.0 | 0.0004 | 0.003 |
| Glucuronate | 0.1 ± 0.0 | 0.0005 | 0.003 |
| N6-acetyllysine | −0..2 ± 0.1 | 0.001 | 0.007 |
| N-acetylserine | 0.2 ± 0.0 | 0.001 | 0.008 |
| Dimethylglycine | 0.2 ± 0.0 | 0.002 | 0.009 |
| Isobutrylcarnitine | 0.1 ± 0.0 | 0.003 | 0.01 |
| N-acetylthreonine | 0.2 ± 0.1 | 0.003 | 0.01 |
| Methylglutarylcarnitine | 0.1 ± 0.0 | 0.003 | 0.01 |
| Arabitol | 0.2 ± 0.1 | 0.003 | 0.01 |
| Serine | − 0.2 ± 0.1 | 0.003 | 0.02 |
| N1-methyl-2-pyridone-5-carboxamide | 0.1 ± 0.0 | 0.005 | 0.02 |
| Tiglyl carnitine | 0.1 ± 0.0 | 0.006 | 0.03 |
| Cis-4-decenoyl carnitine | 0.1 ± 0.0 | 0.007 | 0.03 |
| Ergothioneine | − 0.1 ± 0.0 | 0.007 | 0.03 |
| 2-Methylbutyroylcarnitine | 0.1 ± 0.1 | 0.009 | 0.04 |
| Cortisone | − 0.2 ± 0.1 | 0.01 | 0.05 |
| Butyrylcarnitine | 0.1 ± 0.0 | 0.02 | 0.06 |
| Hexanoylcarnitine | 0.1 ± 0.0 | 0.03 | 0.07 |
| Indolelactate | 0.1 ± 0.0 | 0.04 | 0.10 |
| Glutamine | − 0.2 ± 0.1 | 0.05 | 0.12 |
Metabolites significantly associated with NDM/LDM and with a circulating marker of immune activation (kynurenine/tryptophan) are shown with parameter estimates and standard errors (β ± SE), and with p- and q-values.