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. Author manuscript; available in PMC: 2019 Jun 9.
Published in final edited form as: Int J Numer Method Biomed Eng. 2018 Apr 11;34(6):e2970. doi: 10.1002/cnm.2970

TABLE 1.

Numerical mechanical results for the WT and G229D mutation conditions under 3D sinus rhythm simulation

Parameter Value From Reference WT G229D Difference
LVPP (mmHg) 98-132[1] 110 105 5%
Aortic SP (mmHg) 100-140[1] 107 104 3%
Aortic DP (mmHgg) 60-90[1] 64 60 6%
ESV (mL) 37-57[2] 39 48 23%
EDV (mL) 121-163[2] 88 96 9%
SV (mL) 60-100 49 48 2%
EF (%) 55-68 56 50 11%
LV CO (L/min) 4.0-8.0[3] 6.9 4.8 2%
LV SW (mmHgmL) Not available 3.7 × 103 3.48 × 103 7%
LV ATP consumption rate (s−1) Not available 105 86 18%

LVPP, left ventricle peak pressure; ASP, aortic systolic pressure (systolic blood pressure); ADP, aortic diastolic pressure (diastolic blood pressure); ESV, end systolic volume; EDV, end-diastolic volume; SV, stroke volume; EF, ejection fraction; CO, cardiac output; SW, stroke work; ATP, adenosine triphosphate; WT, wild-type condition.