Table 4.

Effect of treatment with C. scolymus leaves extract on serum lipid profile.

Groups	Cont	HFD	HFD+ EEA  (200mg/kg / bw)	HFD+EEA (400mg/kg/bw)	HFD+ATOR
TG (mmol/L)	1.00 ± 0.29	2.50±0.40∗∗∗	1.13 ± 0.20###	0.8± 0.42###	1.00 ± 0.29###
T-Ch (mmol/L)	1.37 ± 0.12	3.50±0.55∗∗∗	1.60 ± 0.15###	1.70 ± 0.15###	1.62 ± 0.08###
LDL- c (mmol/L)	0.60 ± 0.19	1.80±0.07∗∗∗	1.30± 0.35###	0.80 ± 0.01###	0.45 ± 0.40###
HDL-c (mmol/L)	1.44 ± 0.33	0.50±0.10∗∗∗	0.80 ± 0.33###	1.19± 0.07###¥	0.76 ± 0.08###
AIP	0.95 ± 0.17	6.88±0.14∗∗∗	2.00 ± 0.12###	1.48 ±0.19###¥¥	2.13 ± 0.20###
CRI-I	0.951	7	2	1.42	2.13

HFD groups were orally administered with ethanol extract (EEA) from leaves of C. scolymus and atorvastatin (ATOR) at the doses mentioned earlier for 60 days. Values are given as means ± SD (n = 6). ∗∗∗ p ≤ 0.001 was considered significant compared to control groups; ^### p ≤ 0.001 was considered significant compared to HFD groups; ^¥p ≤ 0.05 and ^¥¥ p ≤ 0.01 were considered significant compared to HFD groups treated with ATOR.