Table 6.
Effect of treatment with C. scolymus leaves extracts on hematological parameters.
| Groups | Cont | HFD | HFD+EEA (200mg/kg/bw) | HFD+EEA (400mg/kg/bw) | HFD+ATOR |
|---|---|---|---|---|---|
| GR (×106) | 6.96 ± 2.37 | 9.13 ± 0.09 | 8.91 ± 0.04¥¥ | 9.00 ± 0.07#¥¥¥ | 8.48 ± 0.04### |
| Hb (g/dL) | 12.55 ± 0.91 | 15.15± 0.91∗∗∗ | 14.85± 0.63 | 15.00 ± 0.21 | 14.80 ± 0.14 |
| HCT(fL) | 36.25± 0.96 | 44.35 ± 1.90∗∗∗ | 43.45 ± 1.90 | 38.55± 0.35#¥¥¥ | 35.75 ± 0.07# |
| VGM(fL) | 50.55 ± 0.63 | 54.9±3.53 | 48.75 ± 2.61 | 50.9 ± 0.00 | 50.55 ± 0.63 |
| TCMH (g/dL) | 13.45± 4.73 | 33.7± 0.15∗∗ | 16.65 ± 0.91## | 16.75 ± 0.07###¥¥¥ | 17.45 ± 0.07## |
| MCHC (g/dL) | 31.6± 1.97 | 33.7± 1.27 | 30.2 ± 0.00 | 32.85 ± 0.21 | 32.85 ± 0.21 |
| GB (×103 /uL) | 6.82 ± 2.06 | 17.45 ± 2.04∗∗ | 10.41 ± 2.06# | 11.2 ±1.12# | 9.46 ±1.08## |
| PLT (×103/uL) | 859 ± 9.23 | 1260 ± 9.34∗∗∗ | 839.5± 8.45## | 914.5± 11.87## | 879 ± 8.21## |
HFD groups were orally administered with ethanol extract (EEA) from leaves of C. scolymus and atorvastatin (ATOR) at the doses mentioned earlier for 60 days. Values are given as means ± SD (n = 6). ∗∗ p ≤ 0.01 and ∗∗∗ p ≤ 0.001 were considered significant compared to control groups; # p ≤ 0.05, ## p ≤ 0.01, and ### p ≤ 0.001 were considered significant compared to HFD groups; ¥¥ p ≤ 0.01 and ¥¥¥ p ≤ 0.001 were considered significant compared to HFD groups treated with ATOR.