Table 7.
Effect of treatment with C. scolymus leaves extract on liver oxidative stress parameters.
| Groups | Liver ROS (fluorescence intensity, FI) | TBARS (nmol MDA/ mg protein) | AOPP (nmol/mg protein) | SOD (U SOD/mg protein) | GSH (ug/mg protein) | GPx (nmol GSH min/mg protein) |
|---|---|---|---|---|---|---|
| Cont | 70.02 ±11.23 | 8.64 ± 0.43 | 4.62 ± 0.01 | 3.79±0.31 | 5.45 ± 0.41 | 6.46 ± 0.60 |
| HFD | 150.30±20.34∗∗∗ | 18.15±0.92∗∗∗ | 8.85±0.08∗∗∗ | 1.91±0.04∗∗∗ | 2.06 ± 0.14∗∗∗ | 4.55 ± 0.28∗∗∗ |
| HFD+EEA(200mg/kg/bw) | 80.23±15.17## | 10.51± 0.56### | 5.12 ± 0.05### | 2.84±0.19### | 4.17± 0.28###¥¥¥ | 5.81 ± 0.17### |
| HFD+EEA(400mg/kg/bw) | 84.17± 16.57### | 9.25 ± 0.61### | 4.53± 0.04### | 2.91±0.04### | 5.10 ± 0.15### | 6.00 ± 0.56###¥ |
| HFD+ATOR | 72.49±13.45### | 10.44 ±1.03### | 4.37 ± 0.05### | 2.49±0.49### | 4.09 ± 0.33### | 5.45 ± 0.15### |
HFD groups were orally administered with ethanol extract (EEA) from leaves of C. scolymus and atorvastatin (ATOR) at the doses mentioned earlier for 60 days. Values are given as means ± SD (n = 6). ∗∗∗ p ≤ 0.001 was considered significant compared to control groups; ### p ≤ 0.001 was considered significant compared to HFD groups; ¥ p ≤ 0.05 and ¥¥¥ p ≤ 0.001 were considered significant compared to HFD groups treated with
ATOR.