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Viral-Directed anti-RABV Compounds
| Compound | Target | EC50 (uM) | CC50 (uM) | SI (CC50/EC50) | Ref. |
|---|---|---|---|---|---|
| Ketamine | vRNA Synthesis | 922.93 ± 68.48 | 3010.69 ± 171.26 | 3.3 | [54, 193] |
| Ribavirin | de novo purine synthesis | 18.55 | >200 | >10 | [57] |
| EICAR | de novo purine synthesis | 0.90 | >200 | >200 | [57] |
| EICNR | de novo purine synthesis | 3.80 | >200 | >50 | [57] |
| Favipiravir | vRdRp | 32.4 | >2500mM | >1000 | [60, 194] |
