Scheme 5.
Reagents and conditions: a. NaH (95%), BnBr, TBAI, THF, reflux, 18 h; b. (i) EtMgBr, THF, −78 °C, (ii) ZnCl2, 2 h, rt; c. 5, Pd(PPh3)4, CuI, THF, reflux, 18 h.
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