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IFP in HL-16 tumors. IFP measured from the ventral side versus IFP measured from the dorsal side for (A) 15 tumors with a homogeneous histology (P < .0001; R2 = .97) and (B) 15 tumors with a heterogeneous histology (P = .0042; R2 = .49). The points represent single tumors. (C) Example of a tumor with homogeneous histology. (D) Example of a tumor with heterogeneous histology, showing that the tissue was divided into compartments by thick bands of connective tissue.
