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. 2019 May;22(5):547–556. doi: 10.22038/ijbms.2019.34246.8139

Table 2.

Calculated amounts of the t 25% , Q 15min and Q 30min for pure carvedilol (CAR), physical mixtures (PM) with drug: polymer ratios of 1:5 and 1:10, and electrosprayed nanosystems (ES) with the drug: polymer ratios of 1:5 and 1:10 at total solution concentrations of 10 %, 15 % and 20 % (w/v)

sample t 25% (min) Q 15 min (%) Q 30 min (%)
CAR 85 3.0 ± 2.9 7.6 ± 2.3
PM 1:5 36 11.0 ± 0.4 21.9 ± 0.6
PM 1:10 44 24.0 ± 3.4 17.5 ± 2.6
ES 1:5 10% 13 28.4 ± 3.1 34.5 ± 2.7
ES 1:5 15% 13 26.5 ± 3.9 36.1 ± 1.1
ES 1:5 20% 18 23.5 ± 1.5 34.7 ± 1.3
ES 1:10 10% 28 11.8 ± 1.0 26.6 ± 1.6
ES 1:10 15% 21 18.5 ± 5.4 32.5 ± 5.0
ES 1:10 20% 4 33.3± 2.6 50.3 ± 4.9