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. 2019 May;22(5):491–498. doi: 10.22038/ijbms.2019.31000.7480

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Overexpression of lncFOXO1 induced cell apoptosis in A549 cells. A549 cells were transfected with pc-FOXO1 and sh-FOXO1 vectors. (A) Cell apoptosis in control and pc-FOXO1 transfected cells was detected by flow cytometry; the protein levels of Bax, cleaved -caspase-3 and Bcl-2 (B) in control and pc-FOXO1 transfected cells and (C) in control and sh-FOXO1 transfected cells were analyzed by western blot assay. Data are presented as the mean ± SD of three independent experiments; * P<0.05.