Table 1.
CMV risk factors for solid organ transplant recipients
Serostatus | Mild risk | Moderate risk | High risk |
---|---|---|---|
D+/R– | XX | ||
D+/R+ | XX | ||
D–/R+ | X | ||
D–/R– | X (from primary infection acquired in the community) | ||
Transplanted organ | |||
Lung | XX | ||
Pancreas | XX | ||
Intestinal | XX | ||
Heart | X | ||
Kidney | X | ||
Liver | X | ||
Induction immunotherapy | |||
Alemtuzumab | XX | ||
ATG | XX | ||
Basiliximab | X | ||
Maintenance immunosuppression | |||
Calcineurin inhibitors/antimetabolites | X | ||
Steroids | X | ||
mTOR inhibitors | X | ||
Mycophenolate mophetil | X (standard dose of =<2 g/day) | X (high dose of ≥3 g/day) |
Notes: XX is higher risk than X for the same risk category
Risk factors for CMV in allogeneic hematopoietic stem cell transplant recipients are listed in the text.
Abbreviations: CMV cytomegalovirus; ATG, anti-thymocyte globulin, mTOR, mammalian target of rapamycin.