Table 2.
Correlation of c-MYC expression with clinical parameters of oral squamous cell carcinoma
| Factors | c-MYC | aaOR (95% CI) | P-value | |
|---|---|---|---|---|
| Low | High | |||
| No. | No. | |||
| (n = 58) | (n=75) | |||
| Tumor size (SD) | 3.16 (1.60) | 2.81 (1.68) | ||
| T classification | ||||
| I/II | 31 | 52 | 1 | |
| III/IV | 27 | 23 | 0.49 (0.24–1.03) | 0.05 |
| N (lymph node) | ||||
| N0/N1 | 48 | 64 | 1 | |
| N2/N3 | 10 | 11 | 0.77 (0.30–1.99) | 0.5 |
| M (metastasis) | ||||
| No | 57 | 75 | 1 | |
| Yes | 1 | 0 | ND | |
| AJCC cancer stage | ||||
| Early stage (I/II) | 25 | 43 | 1 | |
| Advance stage (III/IV) | 33 | 32 | 0.53 (0.26–1.07) | 0.07 |
| Histological grade | ||||
| Well | 4 | 17 | 1 | |
| Moderate/poor | 54 | 58 | 0.25 (0.08–0.81) | 0.02 |
| Death | ||||
| No | 23 | 36 | 1 | |
| Yes | 35 | 39 | 0.55 (0.27–1.15) | 0.11 |
Note: aAdjusted odds ratio (aOR) was controlled for gender and age.
Abbreviation: AJCC, American Joint Committee on Cancer