Table 2.
Positron emission tomography/magnetic resonance imaging results by group
| Group 1: Cardiovascular risk[15] (n = 62) | Group 2: Cocaine users (n = 13) | Group 3: Healthy controls (n = 10) | Group 2 and 3 difference [Sig. (ANCOVA)] | ||
| PET results | |||||
| Target-to-Background ratios (TBR max) | |||||
| Left | NA | 1.77 ± 0.10 | 1.77 ± 0.07 | F (1, 20) = 0.3, P = 0.619 | |
| Right | NA | 1.93 ± 0.09 | 1.76 ± 0.04 | F (1, 20) = 1.9, P = 0.178 | |
| R+L | NA | 1.85 ± 0.09 | 1.76 ± 0.05 | F (1, 20)= -0.2, P = 0.687 | |
| Most diseased segment | |||||
| Left | NA | 2.05 ± 0.15 | 1.99 ± 0.09 | F (1, 20) = 0.0, P = 0.914 | |
| Right | NA | 2.10 ± 0.10 | 1.93 ± 0.07 | F (1, 20) = 1.3, P = 0.259 | |
| R+L | NA | 2.07 ± 0.11 | 1.96 ± 0.08 | F (1, 20) = 0.4, P = 0.560 | |
| MR results | |||||
| Wall thickness (mm; mean, SE) | |||||
| Left | NA | 1.53 ± 0.06 | 1.25 ± 0.04 | F (1, 20) = 7.6, P = 0.012 | |
| Right | NA | 1.50 ± 0.07 1 | 1.20 ± 0.05 | F (1, 19) = 8.3, P = 0.009 | |
| R+L | 1.27 ± 0.04; t(12)2 = 4.12, P = 0.001 | 1.51 ± 0.062 | 1.22 ± 0.04 3 | F (1, 20) = 100, P = 0.005 | |
| Wall area (mm2) | |||||
| Left | NA | 35.67 ± 2.25 | 29.02 ± 1.54 | F (1, 20) = 3.3, P = 0.086 | |
| Right | NA | 34.51 ± 2.061 | 27.37 ± 1.43 | F (1, 19) = 4.9, P = 0.039 | |
| R + L | 32.28 ± 1.43; t(9)4 = -3.13, P = 0.012 | 35.18 ± 1.95 5 | 28.19 ± 1.314 | F (1, 20) = 4.9, P = 0.039 | |
1
n = 12.
2
Cocaine users > Cardiovascular risk: P < 0.001.
3
Cardiovascular disease risk and healthy controls group difference: t(9) = -1.12, P = 0.294.
4
Cardiovascular risk > healthy controls: P < 0.05.
5
Cocaine users and Cardiovascular risk group difference: t(12) = 1.49, P = 0.163. NA: Not available.