Effect of bi-daily subcutaneous administration of 0.5 mg/kg homoharringtonine over 7 days on MDA-MB-468 xenografts in mice. A and B: Tumor volumes, absolute values. C: Tumor volume before and after treatment, mean ± SD. D and E: Mouse weight, absolute values. CTL, control, mice treated with saline water only; HHT, homoharringtonine; D0, beginning of the experiment; D3, D6, D8, D10, day 3, 6, 8 and 10 after the treatment start.