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. 2019 May 15;11(5):2969–2982.

Table 1.

Simplified scoring scale for HIF-1α, VEGF and NICD

Score Criteria

HIF-1α VEGF NICD
0 No positive expression Fewer more than 50% of deep chondrocytes positive No positive expression
1 Some, but fewer more than 50% of deep chondrocytes positive 50% or more of the deep chondrocytes positive Fewer more than 50% of deep chondrocytes positive
2 50% or more of the deep chondrocytes positive Positive chondrocytes in the deep and intermediate zones 50% or more of the deep chondrocytes positive
3 Positive chondrocytes in the deep and intermediate zones, even into the superficial zone Positive chondrocytes in the deep, intermediate and superficial zones Positive chondrocytes in the deep and intermediate zones