Figure 1.

Berberine attenuated the tumorigenesis and reduced liver index. (A) The representative livers from mice with different treatments. The arrows represent the HCC. (B) The numbers and size of tumors in mice in the three groups. The body weight (C) and the liver weight (D) and the liver index (E). (F and G) The expression of HCC biomarker CD34 was measured by immunohistochemistry. Data are presented as the mean ± standard deviation. ***P < 0.001 versus STZ + CD group, ###P < 0.001 versus STZ + HFHC group.