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Berberine inhibited the liver fibrosis. (A) Liver sections in the three groups were stained with Masson staining. The mRNA expressions of Col1A1 (B), α-SMA (C) and TIMP-1 (D) in livers were measured by qPCR. Data are presented as the mean ± standard deviation. GAPDH was used as a load control. *P < 0.05, **P < 0.01, ***P < 0.001 versus STZ + CD group, #P < 0.05, ##P < 0.01 versus STZ + HFHC group.
