Table 2. Risk factor analyses for small-for-size syndrome.
| Variables | Patients without SFSS (n=11) | Patients with SFSS (n=4) | P value |
|---|---|---|---|
| Recipient gender | 0.604 | ||
| Male | 5 | 1 | |
| Female | 6 | 3 | |
| Recipient age* (years) | 64 [39–74] | 50.5 [36–58] | 0.133 |
| Donor gender | 1.000 | ||
| Male | 7 | 2 | |
| Female | 4 | 2 | |
| Donor age* (years) | 38 [29–54] | 50 [36–64] | 0.101 |
| Graft type | 1.000 | ||
| Left | 4 | 1 | |
| Right | 7 | 3 | |
| Background liver disease | 1.000 | ||
| Viral | 5 | 2 | |
| Others | 6 | 2 | |
| Pretransplant AST* (IU/L) | 76 [34–128] | 87.5 [30–200] | 0.947 |
| Pretransplant ALT* (IU/L) | 44 [16–110] | 56 [18–84] | 1.000 |
| Pretransplant ALP* (IU/L) | 552 [295–868] | 420.5 [388–1034] | 0.556 |
| Pretransplant gamma-GTP* (IU/L) | 38 [17–357] | 36 [14–41] | 0.473 |
| MELD score* | 16 [7–23] | 18 [15–23] | 0.261 |
| CTP score* | 11 [10–13] | 11.5 [10–13] | 1.000 |
| Graft volume/standard liver volume* (%) | 43.7 [31.2–67.1] | 43.05 [38.0–56.4] | 0.845 |
| Graft recipient weight ratio* (%) | 0.79 [0.65–1.19] | 0.845 [0.72–1.04] | 0.896 |
| Simultaneous splenectomy at transplant | 0.154 | ||
| Yes | 10 | 2 | |
| No | 1 | 2 | |
| Intraoperative blood loss* (mL) | 3,698 [875–18,450] | 6,840 [1,227–15,500] | 0.557 |
| Operation time* (min) | 708 [509–978] | 713.5 [562–919] | 0.948 |
| Portal pressure at the end of the operation* (mmHg) | 16 [14–19] | 15.5 [13–21] | 0.791 |
| Portal venous flow per gram of graft* (mL/min/g) | 2.97 [1.53–7.42] | 3.02 [2.17–7.03] | 1.000 |
| Pretransplant M2BPGi* (C.O.I.) | 8.83 [3.04–20.34] | 18.54 [7.64–24.49] | 0.103 |
| POD 1 M2BPGi* (C.O.I.) | 1.48 [0.93–6.79] | 2.06 [0.9–7.63] | 1.000 |
| POD 3 M2BPGi* (C.O.I.) | 1.07 [0.47–2.93] | 1.96 [1.47–2.05] | 0.067 |
| POD 7 M2BPGi* (C.O.I.) | 1.08 [0.46–2.98] | 4.15 [3.06–4.74] | 0.005 |
| POD 7 AST* (IU/L) | 35 [22–88] | 224.5 [39–557] | 0.031 |
| POD 7 ALT* (IU/L) | 94 [39–239] | 445.5 [40–701] | 0.117 |
| POD 7 ALP* (IU/L) | 218 [183–43499] | 321.5 [190–446] | 0.473 |
| POD 7 gamma-GTP* (IU/L) | 91 [45–364] | 146 [42–582] | 0.648 |
*, numerical data are expressed as a median [range]. ALT, alanine transaminase; ALP, alkaline phosphatase; AST, aspartate transaminase; C.O.I., cutoff index; CTP, Child-Turcotte-Pugh; gamma-GTP, gamma-glutamyl transpeptitase; M2BPGi, Wisteria floribunda agglutinin positive human Mac-2 binding protein glycosylation isomer; MELD, Model for End-Stage Liver Disease; POD, postoperative days; SFSS, small-for-size syndrome.