Table 3.
Effect of plant steroids and fluticasone on the adrenal and thymus gland indices in the cotton pellet-induced granuloma model.
| Ligands | Adrenal index | Thymus index |
|---|---|---|
| Control | 3.1 ± 0.2a | 22 ± 3a |
| PC | 4.9 ± 0.4 | 39 ± 2 |
| PC-GA | 4.9 ± 0.2 | 39 ± 2 |
| PC-GS | 4.4 ± 0.3 | 37 ± 2 |
| PC-BA | 4.3 ± 0.2 | 34 ± 3 |
| PC-WA | 3.9 ± 0.1 | 29 ± 1a |
| PC-DG | 4.3 ± 0.2 | 35 ± 3 |
| PC-FC | 3.3 ± 0.2a | 26 ± 1a |
Values were expressed as mean ± SEM (n = 6) and analyzed by one-way ANOVA followed by Tukey's test. Results were considered significant if p values were less than 0.5. Results were considered significant if p values were less than 0.5. aSignificant compared to positive control (PC). PC-GA: PC treated with glycyrrhetinic acid; PC-GS: PC treated with guggulsterone; PC-BA: PC treated with boswellic acid; PC-WA: PC treated with withaferin A; PC-DG: PC treated with diosgenin; PC-FC: PC treated with fluticasone.