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Effect of CUP or PT on Glu-induced PC12 cell death. PC12 cells were incubated for 24 h in medium containing 8 mM Glu + CUP ((a) 2–60 μg/mL) or PT ((b) 2–60 μg/mL). The control medium (Ctrl) contained no Glu. Survival rate calculated as the %MTT activity relative to control PC12 cells. Data are presented as the mean ± SEM (n = 6). †††P < 0.001 vs. Ctrl; ∗∗P < 0.01 and ∗∗∗P < 0.001 vs. Glu: one-way ANOVA + Dunnett's test.
