Table 1.

Summary of Clinical Features in the Affected Individuals

Case ID	Family 1_IV:12	Family 1_IV:13	Family 1_IV:16	Family 2_IV:7	Family 2_IV:8	Family 2_IV:10	Family 2_IV:12
Gender	male	male	female	male	male	male	male
Age	15 years	12 years	5 years	28 years	26 years	24 years	16 years
ID	P	P	P	P	P	P	P
Epilepsy	P	P	A	P	P	P	P
GDD	P	P	P	P	P	P	P
MRI brain	NA	arachnoid granulation	NA	NA	NA	N	N
Other features		mild dysmorphism, ADHD		mild dysmorphism	prune belly syndrome	prune belly syndrome, unilateral renal agenesis, macrocephaly	ADHD, CHD, macrocephaly

Abbreviations are as follows: A, absent; ADHD, attention deficit hyperactivity disorder; CHD, congenital heart disease; N, normal; NA, not available; and P, present.