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. 2019 May 23;90:1721. doi: 10.4102/jsava.v90i0.1721

TABLE 2.

Summary of synovial fluid cytology, clinical chemistry and growth factor concentrations for control and osteoarthritis group (mean ±SD).

Day NCC (cells/μL) Neutrophils (%) TP (g/L) SAA (mg/L) PDGF-BB (pg/mL) TGF-β1 (pg/mL)
Day 0
Control 111.60 ± 39.89 1.60 ± 2.45 15.48 ± 6.31 0.00 ± 0.00 - -
OA 87.40 ± 53.64 5.40 ± 8.50 14.22 ± 2.56 0.00 ± 0.00 - -
Day 1
Control 22940.00 ± 11103.28*,*** 83.40 ± 2.70*,**** 46.64 ± 11.11* 0.00 ± 0.00 390.47 ± 82.15**,*** 4021.27 ± 783.00**,***,****
OA 20464.00 ± 12055.93*,*** 71.20 ± 5.40*,**** 39.06 ± 7.10* 0.00 ± 0.00 302.27 ± 47.44** 2792.48 ± 615.46**,***,****
Day 2
Control 13212.00 ± 3413.46* 64.00 ± 4.00*,** 30.18 ± 11.55* 0.00 ± 0.00 - -
OA 7372.00 ± 6122.10 38.80 ± 14.32*,** 22.46 ± 5.90* 0.00 ± 0.00 - -
Day 5
Control 3654.00 ± 2037.59*** 14.80 ± 11.86**** 20.56 ± 8.02 0.95 ± 2.14 316.42 ± 45.69*** 851.73 ± 351.82***,****
OA 1660.40 ± 1250.72*** 8.20 ± 15.54**** 16.54 ± 6.09 0.00 ± 0.00 318.06 ± 37.82 678.35 ± 289.58***,****
Day 21
Control 207.60 ± 49.90 2.60 ± 1.67 17.14 ± 6.61 0.00 ± 0.00 - -
OA 213.00 ± 123.80 5.20 ± 6.97 12.18 ± 3.18 0.00 ± 0.00 - -
Day 56
Control 224.80 ± 71.94 10.80 ± 11.16 14.62 ± 4.51 0.00 ± 0.00 - -
OA 95.60 ± 71.40 4.20 ± 6.79 13.78 ± 3.26 0.00 ± 0.00 - -

OA, Osteoarthritis; NCC, nucleated cell count; TP, total protein; SAA, Serum amyloid A; PDGF, platelet-derived growth factor; TGF-b1, transforming growth factor-beta 1.

*

, Statistically significant differences from baseline, within a given group (p < 0.05).

**

, Statistically significant differences between groups on a specific day (p < 0.05).

***

, Statistically significant correlation between NCC (cells/μL) and PDGF-BB/TGF-b1 (p < 0.05).

****

, Statistically significant correlation between Neutrophils (%) and PDGF-BB/TGF-b1 (p < 0.05).