Table 1. Baseline characteristics.
| TXA group
N=93 |
Placebo group
N=94 |
|
|---|---|---|
| Maternal Age - years mean (SD) | 27.8 (5.6) | 27.0 (5.6) |
| Body Mass Index- kg/m² mean (SD) | 28.5 (3.1) | 29.9 (4.8) |
| Gestational age at birth–weeks mean (SD) | 38.3 (2.8) | 38.2 (3.4) |
| FetalBirthweight – g. mean (SD) | 3185 (695.2) | 3222 (843.8) |
| Hemoglobin - g/dL + mean (SD) | 10.8 (1.8) | 11.4 (1.6) |
| Fibrinogen - g/L mean (SD) | 3.6 (1.1) | 3.5 (1.2) |
| Platelet count -10³/mm³ mean (SD) | 229.3 (80.4) | 233.7 (80.1) |
| Blood lost mL mean (SD) | 863.2 (270.7) | 893.1 (219.9) |
| Vaginal births Labor stages - First stage(hrs)
Mean (SD) [N] Second stage (min) Third stage (min) |
6.7 (4.3) [71]
*
40.5 (26.0) [67] * 10.9 (9.1) [66] * |
7.8 (4.1) [68]
*
48.5 (31.6) [66] * 13.5 (12.4) [65] * |
| Parity : N (%) Nullipara
Multipara |
57 (61.3 %)
36 (38.7 %) |
60 (63.8 %)
34 (36.2 %) |
| Type of delivery: N (%) Vaginal
Caesarean |
65 (69.9%)
28 (30.1%) |
65 (69.2%)
29 (30.8%) |
| Primary cause PPH: N (%) Placenta previa
Surgical trauma /tears Uterine atony Other Unknown |
11 (11.8%)
10 (10.8%) 71 (76.3%) 1 (1.1%) 0 (0%) |
14 (14.9%)
19 (20.2%) 59 (62.8%) 1 (1.1%) 1 (1.0%) |
| Preeclampsia: N (%) Yes
No |
11 (11.8 %)
82 (88.2 %) |
7 (7.4 %)
87 (92.6 %) |
| Chorioamnionitis: N (%) Yes
No |
5 (5.4 %)
88 (94.6 %) |
6 (6.4 %)
88 (93.6 %) |
| Placental abruption: N (%) Yes
No |
9 (9.7 %)
84 (90.3 %) |
5 (5.3 %)
89 (94.7 %) |
| Anaemia: N(%) Yes
No |
34 (36.6 %)
59 (63.4 %) |
23 (24.5 %)
71 (75.5 %) |
| Previous PPH: N (%) Yes
No |
3 (3.2 %)
90 (96.8 %) |
6 (6.4 %)
88 (93.6 %) |
| Hematologic disease N (%) Yes
No |
1 (1.1 %)
92 (98.9 %) |
0 (0%)
94 (100 %) |
| Treatment with antithrombotics N (%) Yes
No |
0 (0%)
93 (100 %) |
2 (2.1 %)
92 (97.9 %) |
* Patients vaginal delivery; + p-value Wilcoxon-Mann-Whitney-Test: 0.01