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. 2019 Jun 4;4(1):e000248. doi: 10.1136/bmjophth-2018-000248

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: http://creativecommons.org/licenses/by/4.0/.

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The process towards genetic-guided treatment in the field of ophthalmology. The figure indicates different procedures of sample collection, nucleic acid extraction, sample preparation, sequencing, bioinformatics, analysis and report writing, indication to the eye surgeon for specific drug usage for specific microorganism and metagenomic-guided eye treatment on the patient. Being highly specific and cost-effective, metagenomics could be potentially used in ophthalmology in the near future.