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. 2019 Sep;14(9):1530–1535. doi: 10.4103/1673-5374.255974

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Copyright: © Neural Regeneration Research

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Beneficial effects of sodium butyrate (SB) on radiation-induced decreases of doublecortin (DCX)-positive cells in the subgranular zone (SGZ) of the supra- and infra-pyramidal blades of the dentate gyrus (DG) of the hippocampus after 30 days radaition exposure.

(A) DCX immunoreactivity (arrows) in the DG of the hippocampus. Scale bar: 50 μm. (B) Quantification of DCX-immunoreactive cells. SB attenuated radiation-induced decrease in neurogenesis. The data are shown as the mean ± SE (n = 6/group). *P < 0.05 (one-way analysis of variance followed by Student-Newman-Keuls post hoc test).