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. Author manuscript; available in PMC: 2019 Nov 8.
Published in final edited form as: J Med Chem. 2018 Oct 18;61(21):9611–9620. doi: 10.1021/acs.jmedchem.8b01076

Figure 2.

Figure 2.

A) HIV-1 Rev-RRE dependent nuclear export reporter activity assay in transiently transfected 293T cells measured as expression of HIV-1 p24 protein using ELISA. The assay was performed in the presence of 30 μM BPs. B) Structure of 4A5. C) Dose-response curves of HIV-1 Rev-RRE reporter activity and cell viability of HEK 293T cells with 4A5. Data points are mean ± standard deviation.