Fig. 3.

Effects of tedizolid and comparator antibiotics on S. aureus TSST-1 toxin expression. Levels of TSST-1 were quantified from culture supernatants by ELISA. Each panel shows TSST-1 expression levels following treatment with the indicated antibiotic in (a–c) CDC 368–04 and in (d–f) MSSA 04–002. Bars represent average toxin expression±standard error from three biological replicates. Asterisks denote statistical significance of (*) P<0.05, (**) P<0.01, (***) P<0.001 and (****) P<0.0001 compared to the no treatment (NT) vehicle control at each corresponding timepoint.