Fig. 2.
CCNE1 two-color FISH in a representative serous tubal intraepithelial carcinoma. The H&E of the lesion is shown at the left panel. Red signals: CCNE1 probe; green signal: CEP control probe; blue: nuclear staining with DAPI. There are many serous tubal intraepithelial carcinoma cells exhibiting CCNE1 amplification (big red dots).