Figure 5. Summarizing the differential genetic and epigenetic progression mechanisms from normal stage to early stage, early stage to middle stage, and middle stage to advanced stage LADC and LSCC.

The figure summarizes the differential genetic and epigenetic progression mechanisms caused by core signaling pathways within each connective stage of LADC and LSCC. The red font with dash-line rectangular blocks denote the differential function between LADC and LSCC.