Table 1.
Baseline characteristics of patients by treatment group
| Characteristics | 10 mL/kg (n=39) |
20 mL/kg (n=34) |
| Age (months) | ||
| Median (IQR) | 11 (1–35) | 2 (1–17) |
| Gender, n (%) | ||
| Male | 24 (61.5) | 18 (52.9) |
| Female | 15 (38.5) | 16 (47.1) |
| Weight (kg) | ||
| Median (IQR) | 9 (5–13) | 5 (4–10) |
| Shock criteria met, n (%) | ||
| CRT* only | 30 (76.9) | 30 (88.2) |
| Hypotension only | 2 (5.1) | 2 (5.9) |
| CRT* and hypotension | 1 (2.6) | 2 (5.9) |
| Neither | 6 (15.4) | 0 (0.0) |
| Systolic BP (mm Hg) | ||
| Median (IQR) | 102 (91–114) | 104 (89–115) |
| CRT (s) | ||
| Median (IQR) | 3 (3–4) | 3 (3–4) |
| PIM2r (2016) score (%) | ||
| Median (IQR) | 2.1 (1.6–2.7) | 2.0 (1.6–2.5) |
| Infection confirmed, n (%) | ||
| No | 19 (48.7) | 17 (50.0) |
| Yes | 20 (51.3) | 17 (50.0) |
| Organism | ||
| Bacterial, n (%) | 5 (31.3) | 8 (50.0) |
| Escherichia coli | 1 (6.3) | 4 (25.0) |
| Enterococcus faecalis | 2 (12.5) | 0 (0.0) |
| Group A streptococcus | 1 (6.3) | 1 (6.3) |
| Group B streptococcus | 0 (0.0) | 1 (6.3) |
| Staphylococcus aureus | 1 (6.3) | 0 (0.0) |
| Meningococcus | 0 (0.0) | 1 (6.3) |
| Gram-positive coccus (unspecified) | 0 (0.0) | 1 (6.3) |
| Viral, n (%) | 10 (62.5) | 8 (50.0) |
| Respiratory syncytial virus | 5 (31.3) | 3 (18.8) |
| Rhinovirus | 2 (12.5) | 3 (18.8) |
| Influenza A | 0 (0.0) | 1 (6.3) |
| Metapneumovirus | 1 (6.3) | 0 (0.0) |
| Enterovirus | 1 (6.3) | 1 (6.3) |
| Rotavirus | 1 (6.3) | 0 (0.0) |
| Others, n (%) | 1 (6.3) | 0 (0.0) |
| Falciparum malaria | 1 (6.3) | 0 (0.0) |
*CRT≥3 s.
BP, blood pressure; CRT, capillary refill time; PIM2r, Paediatric Index of Mortality, recalibrated version.