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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Bone Miner Res. 2019 Jan 28;34(4):681–698. doi: 10.1002/jbmr.3635

Figure 4: Gut microbiome supplementation following antibiotics affects intestinal microbial composition.

Figure 4:

12-week-old BALB/c male mice were untreated (controls) or treated with ABX for 2 weeks. Post-ABX mice were either given sterile water (Veh) or supplemented with L. reuteri (LR), Lactobacillus rhamnosus GG (LGG) or non-pathogenic Escherichia coli (EC) for 4 weeks. A) Relative abundances of bacterial communities following gut supplementation. B) PCoA plot of fecal microbiome, Bray-Curtis analysis performed. Analysis of operational taxonomic units (OTUs) classified to the phylum’s C) Firmicutes to Bacteroidetes ratio D) Firmicutes, Bacteroidetes and Verrucomicrobia. n = 8,9,10,4,5 respectively per group, Values are average ± SEM. Statistical analysis of operational taxonomic units were performed by 1-way ANOVA with Tukey posttest. **** p<0.0001; *** p<0.001; ** p<0.01.