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. Author manuscript; available in PMC: 2020 Sep 2.
Published in final edited form as: Behav Brain Res. 2019 Apr 24;369:111923. doi: 10.1016/j.bbr.2019.111923

Figure 3.

Figure 3

Six weeks of exercise prevented stress-induced exaggerated freezing. Sedentary (Sed) and voluntary wheel running (Run) rats remained in their home cages (No stress) or were exposed to 100 uncontrollable tail shocks (Stress). Shock-elicited freezing behavior was measured 24 h later. (A) Levels of freezing are shown in 2 min blocks. (B) Average levels of freezing over the entire test. Freezing did not differ between rats in metestrus and diestrus (Met/Di) or proestrus and estrus (Pro/Est) phases of the estrous cycle. Symbols represent values of individual rats in either Met/Di (white diamonds, n=4/group) or Pro/Est (gray triangles, n=4/group). Group means Met/Di: Sed No Stress = 44.2, Sed Stress = 59.4, Run No Stress = 57.7, Run Stress = 40.2. Group means Pro/Est: Sed No Stress = 36.0, Sed Stress = 68.4, Run No Stress = 44.1, Run Stress = 50.1. Bars represent group means (regardless of estrous phase) ± SEM. Repeated measures ANOVA: *p < 0.05 Sed No Stress versus Sed Stress; **p < 0.01 Sed No Stress versus Sed Stress; Φp < 0.05 Run Stress versus Sed Stress; Ωp < 0.05 Run No Stress versus Sed Stress. ANOVA: **p < 0.01 Sed Stress relative to Run Stress and Sed No Stress.