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A, B) Bacteremia model. BALB/c mice (n = 8) were immunized with individual antigens (20 or 200 micrograms) and then challenged with a S. aureus IV infection. Mice were monitored daily and euthanized when moribund. No benefit was observed in follow up studies in the bacteremia model. Increasing the antigen dose 10-fold did not result in a statistically significant benefit.
