Fig 7. Structural model for the role of cytoplasmic P10 in nuclear lysis.

P10 (blue) presents as a thin filamentous structure that develop into a complex network of P10 tubules that wrap around the nucleus forming a peri-nuclear cage-like structure. The cage-like structure continue to remodel over time and by 96 hpi most P10 has coalesced into a polarised mass. This final remodelling is associated with loss of nuclear integrity, resulting in nuclear lysis and release of occlusion bodies.