Figure 2.

Methylation pattern across tissues and the between-tissue differences across individuals. (2a). Red circles indicate measured placenta beta values vs. measured cord blood beta values (x = measured placenta beta values, y = measured cord blood beta values), and purple circles indicate measured placenta beta values vs. SVM predicted placenta beta values (x = measured placenta beta values, y = predicted placenta beta values by single-CpG-based SVM and leave-one-out cross-validation). R²(raw) = CpG-wise R² between measured methylation beta values in the placenta and measured methylation beta values in the cord blood. R²(svm) = CpG-wise R² between measured methylation beta values in the placenta and predicted methylation beta values in the placenta by single-CpG-based SVM and leave-one-out cross-validation.