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. 2019 Jun 4;13(1):172–191. doi: 10.1080/19336950.2019.1619436

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Sensitivity of Capsaicin- and Cannabinoid-induced conductances to Capsazepine. A, B.

Current development graph (A) and extracted current/voltage relationship (B) in HEK-TRPV1 stimulated with 50 nM Capsaicin and then application of 10 µM Capsazepine (CPZ). C, D. Protocol as in (A), but with stimulus of 30 μM Cannabidiol (CBD). The recording solutions were Ca 0 internally and externally and the n determinations were from 5 to 6 patches. The current development graphs (A and C) were generated by extracting currents at the voltages of −80 mV and +80 mV.