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. 2019 May 13;14(7):721–739. doi: 10.1080/15592294.2019.1614417

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© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 6. — DMR developmental timelines. Top 100 most statistically significant DMR developmental alterations (E13 primordial germ cells, E16 prospermatogonia, P10 spermatogonia, pachytene spermatocyes). The DMRs are separated into two groups based on whether scaled RPKM read depth is elevated in the control or in the exposure lineage. The vinclozolin percent (%) scaled RPKM read depth developmental timelines are presented. (a,b) Top 100 DMRs in the primordial germ cell comparison. (c,d) Top 100 DMRs in the E16 prospermatogonia comparison. (e,f) Top 100 DMRs in the P10 spermatogonia comparison. (g,h) Top 100 DMRs in the pachytene spermatocytes comparison.