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. 2019 Jun 10;15(6):e1007671. doi: 10.1371/journal.ppat.1007671

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© 2019 Ambite et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 8 — Tentative upstream regulators of the transcriptional response to E. coli 83972pap and E. coli 83972fim were identified, using the IPA upstream regulator analysis. The -log (p-value) describes the prevalence of regulator-associated genes in data set and a positive z-score predicts activation while a negative score predicts inhibition. A. Prediction of IRF-7 as a transcriptional regulator of the response to E. coli 83972pap by activated downstream genes. B. Top predicted transcriptional regulators for the E. coli 83972pap dataset from P V at the time of symptoms red = activated, blue = inhibited). C,D. Predicted transcriptional regulators for E. coli 83972fim in the dataset from P I, 3 hours (C) or 24 hours (D) after inoculation. E. Prediction of MYC as a transcriptional regulator of the response to E. coli 83972fim by inhibited downstream genes.