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. 2019 Apr 29;67(8):1571–1597. doi: 10.1002/glia.23630

Table 8.

Gene ontology (GO) terms enriched in genes affected by EGFR inhibition and glioblastomaa

Term ID Term name FDR
GO terms shared by genes affected by EGFR inhibition and glioblastoma
GO:0007049 Cell cycle 3.03E−10
GO:0007067 Mitotic nuclear division 2.99E−06
GO:0051301 Cell division 3.63E−05
GO terms only enriched in genes affected by EGFR inhibition
GO:0006260 DNA replication 9.85E−09
GO:0007059 Chromosome segregation 1.83E−06
GO:0000122 Negative regulation of transcription from RNA polymerase II promoter 6.01E−05
GO:0000082 G1/S transition of mitotic cell cycle 8.51E−05
GO:0000070 Mitotic sister chromatid segregation 8.56E−05
GO:0006974 Cellular response to DNA damage stimulus 1.21E−04
GO:0007399 Nervous system development 2.81E−04
GO:0016126 Sterol biosynthetic process 8.09E−04
GO:1904874 Positive regulation of telomerase RNA localization to Cajal body 8.98E−04
GO:0007018 Microtubule‐based movement 0.001232
GO:0006270 DNA replication initiation 0.001693
GO:0006730 One‐carbon metabolic process 0.004834
GO:0007411 Axon guidance 0.005193
GO:0008203 Cholesterol metabolic process 0.012354
GO:0043407 Negative regulation of MAP kinase activity 0.042922
GO:0006694 Steroid biosynthetic process 0.046516
GO:0006695 Cholesterol biosynthetic process 0.047637
a

GO terms are ranked by FDR.