Table 3.
Mean initial and final scores for each PMS symptom in each patient in HORMONE (A) and PLACEBO (B) groups Blank spaces indicate lack of symptom appearance in the patient. (I = Initial, F = Final).
| HORMONE group | Pt No |
1 |
2 |
6 |
13 |
14 |
21 |
26 |
28 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean score Initial/Final | I | F | I | F | I | F | I | F | I | F | I | F | I | F | I | F | |
| Symptoms | |||||||||||||||||
| Headache | 3.3 | 0.0 | 2.4 | 1.4 | 5.1 | 1.8 | 6.1 | 6.9 | 4.4 | 3.3 | 2.0 | 0.0 | 8.7 | 1.3 | |||
| Breast tenderness or swelling | 6.4 | 0.0 | 3.5 | 3.3 | 5.3 | 7.4 | 8.4 | 8.4 | 2.0 | 0.0 | 10.0 | 1.3 | 5.8 | 4.3 | |||
| Menstrual cramps/Joint or muscle pain | 8.6 | 7.2 | 3.5 | 3.8 | 5.2 | 5.5 | 2.6 | 5.8 | 5.2 | 6.2 | 5.4 | 0.0 | 8.0 | 1.3 | 5.8 | 4.3 | |
| Bloatedness | 9.3 | 7.8 | 5.5 | 0.3 | 6.0 | 5.9 | 10.0 | 10.0 | 2.1 | 0.0 | 10.0 | 1.3 | |||||
| Hot flushes | 7.7 | 2.0 | 1.3 | 4.1 | 4.4 | 0.0 | 9.2 | 0.0 | 2.1 | 1.8 | |||||||
| Nausea/diarrhea/constipation | 8.9 | 8.0 | 1.4 | 6.5 | 5.7 | 10.0 | 9.8 | 1.3 | |||||||||
| Palpitations | 6.8 | 0.0 | 2.0 | 8.0 | 2.3 | 0.0 | 7.6 | 0.0 | |||||||||
| Weight gain | 7.2 | 0.2 | 3.9 | 5.6 | 3.5 | 2.4 | 10.0 | 9.8 | 10.0 | 0.0 | |||||||
| Confusion/lack of concentration/feeling out of control | 6.7 | 0.0 | 2.8 | 0.3 | 4.1 | 7.6 | 5.6 | 4.4 | 10.0 | 0.7 | |||||||
| Tearful | 1.8 | 0.0 | 3.6 | 7.9 | 8.1 | 0.7 | |||||||||||
| Dizziness | 4.8 | 0.0 | 2.6 | 0.0 | 0.9 | 5.6 | 9.7 | 0.0 | |||||||||
| Acne | 2.7 | 1.2 | 7.3 | 0.7 | 7.3 | 9.3 | 7.6 | 0.0 | 1.7 | 1.4 | |||||||
| Food cravings | 7.8 | 6.5 | 4.0 | 3.9 | 7.7 | 4.4 | 7.0 | 5.4 | 10.0 | 10.0 | 4.6 | 0.0 | 10.0 | 0.7 | 3.2 | 0.0 | |
| Forgetfulness | 3.2 | 0.0 | 2.8 | 3.1 | 4.6 | 0.0 | 6.7 | 0.0 | |||||||||
| Anger/Irritability | 9.0 | 6.0 | 3.8 | 3.5 | 2.7 | 0.0 | 5.9 | 9.0 | 6.2 | 6.1 | 1.3 | 0.0 | 9.9 | 0.7 | 1.9 | 0.0 | |
| Depression | 9.1 | 2.0 | 4.0 | 9.1 | 5.3 | 1.6 | 8.7 | 0.0 | |||||||||
| Arguments/violent tendencies | 8.0 | 7.3 | 2.5 | 0.9 | 6.3 | 0.7 | 7.8 | 3.3 | |||||||||
| Anxiety/tension | 4.2 | 3.0 | 5.8 | 4.6 | 5.8 | 9.5 | 6.4 | 1.0 | 10.0 | 2.0 | |||||||
| Mood swings | 8.4 | 7.1 | 3.7 | 1.9 | 2.2 | 0.0 | 3.3 | 8.9 | 5.4 | 0.0 | 10.0 | 2.0 | 1.9 | 0.0 | |||
| Increased appetite | 7.4 | 7.2 | 6.3 | 6.1 | 6.1 | 3.5 | 5.9 | 4.3 | 10.0 | 10.0 | 4.9 | 0.0 | 10.0 | 1.3 | 3.7 | 0.0 | |
| Over-sensitivity | 7.7 | 5.9 | 3.0 | 1.1 | 2.0 | 0.0 | 6.4 | 8.8 | 7.8 | 4.4 | 10.0 | 0.0 | 1.9 | 0.0 | |||
| Isolation/less interest in daily activities (work, school, Friends, Hobbies) | 9.0 | 1.5 | 5.2 | 1.0 | 5.5 | 0.0 | 4.0 | 6.0 | 5.6 | 2.0 | 5.0 | 0.0 | 10.0 | 4.3 | 1.5 | 0.0 | |
| Fatigue, lack of energy | 10.0 | 7.4 | 6.7 | 5.6 | 8.4 | 4.6 | 7.1 | 8.3 | 9.8 | 1.2 | 3.9 | 0.0 | 10.0 | 4.3 | 2.7 | 0.0 | |
| Slept more/difficulty to get up/trouble falling asleep or staying asleep | 6.4 | 3.3 | 4.8 | 0.3 | 7.7 | 4.6 | 6.4 | 5.9 | 9.8 | 4.2 | 2.8 | 0.0 | 10.0 | 4.3 | 2.8 | 0.0 | |
| Reduced productivity/inefficiency at work/school/home/daily routine, as a result of any of the above | 4.5 | 2.0 | 2.8 | 1.9 | 2.5 | 4.4 | 8.6 | 2.0 | 3.0 | 0.0 | 10.0 | 4.3 | |||||
| Avoidance/less participation in hobbies/social activities, as a result of any of the above | 3.6 | 1.5 | 2.2 | 0.0 | 10.0 | 4.3 | |||||||||||
| B. PLACEBO group | Pt No |
3 |
4 |
11 |
17 |
20 |
30 |
33 |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Score Initial/Final | I | F | I | F | I | F | I | F | I | F | I | F | I | F | |
| Symptoms | |||||||||||||||
| Headache | 4.0 | 2.0 | 2.4 | 3.1 | 5.1 | 3.7 | |||||||||
| Breast tenderness or swelling | 3.3 | 2.3 | 6.1 | 9.4 | 6.0 | 3.2 | 5.2 | 3.0 | 7.0 | 4.0 | 8.5 | 0.0 | |||
| Menstrual cramps/Joint or muscle pain | 4.7 | 4.6 | 9.1 | 9.4 | 6.4 | 3.2 | 5.8 | 5.7 | 9.0 | 6.5 | 6.4 | 0.7 | |||
| Bloatedness | 4.0 | 3.7 | 2.4 | 1.7 | 6.9 | 0.0 | 4.5 | 2.8 | 9.8 | 6.5 | 6.1 | 0.4 | |||
| Hot flushes | 2.3 | 4.3 | 5.4 | 8.0 | 3.9 | 0.0 | 3.0 | 0.0 | 7.7 | 0.0 | |||||
| Nausea/diarrhea/constipation | 2.3 | 4.1 | 6.7 | 1.7 | |||||||||||
| Palpitations | |||||||||||||||
| Weight gain | 7.7 | 2.9 | 1.9 | 1.5 | 2.7 | 0.0 | 4.7 | 0.0 | 5.8 | 0.4 | |||||
| Confusion/lack of concentration/feeling out of control | 8.3 | 6.6 | 5.5 | 0.0 | 7.2 | 0.0 | 5.4 | 0.0 | 2.3 | 0.9 | |||||
| Tearful | 1.7 | 0.0 | 1.1 | 7.1 | 4.6 | 0.0 | 9.3 | 0.0 | 6.6 | 0.7 | |||||
| Dizziness | |||||||||||||||
| Acne | 0.9 | 0.0 | 1.9 | 1.6 | 3.5 | 0.7 | 2.0 | 6.5 | |||||||
| Food cravings | 10.0 | 10.0 | 7.4 | 6.9 | 3.8 | 3.5 | 10.0 | 0.0 | 6.7 | 0.7 | |||||
| Forgetfulness | 2.1 | 2.9 | 6.3 | 0.0 | 3.2 | 0.0 | 1.0 | 0.4 | |||||||
| Anger/Irritability | 1.9 | 1.9 | 5.0 | 7.4 | 8.3 | 0.0 | 4.5 | 2.2 | 10.0 | 5.7 | 7.4 | 0.7 | |||
| Depression | 3.7 | 0.0 | 6.7 | 0.7 | 2.9 | 2.0 | |||||||||
| Arguments/violent tendencies | 1.9 | 1.0 | 3.4 | 5.7 | 6.8 | 0.0 | 2.5 | 1.0 | 8.0 | 4.0 | 6.7 | 0.0 | |||
| Anxiety/tension | 2.9 | 4.3 | 3.9 | 0.0 | 7.4 | 0.7 | 1.8 | 0.7 | |||||||
| Mood swings | 5.0 | 4.3 | 7.3 | 0.0 | 2.7 | 0.3 | 8.7 | 0.0 | 7.4 | 0.7 | |||||
| Increased appetite | 2.9 | 3.7 | 10.0 | 6.6 | 6.8 | 0.8 | 2.3 | 4.0 | 4.8 | 0.0 | 6.9 | 1.6 | |||
| Over-sensitivity | 6.0 | 8.0 | 8.1 | 3.5 | 2.7 | 0.0 | 4.7 | 0.0 | 6.1 | 1.8 | |||||
| Isolation/less interest in daily activities (work, school, Friends, Hobbies) | 3.3 | 1.7 | 8.6 | 7.4 | 9.2 | 0.0 | 6.1 | 1.8 | |||||||
| Fatigue, lack of energy | 3.9 | 4.6 | 10.0 | 8.9 | 9.8 | 0.0 | 1.7 | 0.0 | 7.8 | 7.3 | 8.1 | 1.8 | 5.0 | 2.9 | |
| Slept more/difficulty to get up/trouble falling asleep or staying asleep | 4.0 | 3.7 | 7.9 | 5.7 | 10.0 | 0.0 | 4.3 | 3.7 | 5.9 | 0.7 | |||||
| Reduced productivity/inefficiency at work/school/home/daily routine, as a result of any of the above | 2.3 | 0.7 | 9.4 | 7.1 | 8.1 | 0.0 | 8.3 | 0.0 | 5.4 | 0.7 | |||||
| Avoidance/less participation in hobbies/social activities, as a result of any of the above | 9.7 | 5.0 | 8.6 | 0.0 | 6.7 | 0.0 | 5.4 | 0.7 | |||||||